New fat-fighting pill has also reverses diabetes
- Friday, August 28, 2009, 2:19
- Health News
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Scientists hope tests in mice lead to pill to combat fat, cholesterol, and diabetes.
Researchers searching for a cure for obesity said they have developed a drug that not only makes mice lose weight, but reverses diabetes and lowers their cholesterol, too.
The drug, which they have dubbed fatostatin, stops the body from making fat, instead releasing the energy from food. They hope it may lead to a pill that would fight obesity, diabetes and cholesterol, all at once.
Scientists are painfully aware that drugs that can make mice thin do nothing of the sort in humans. A hormone called leptin can make rats and mice drop weight almost miraculously but does little or nothing for an obese person, for instance.
Fatostatin is a small molecule, meaning it has the potential to be absorbed in pill form. “Fatostatin blocked increases in body weight, blood glucose, and hepatic (liver) fat accumulation in (genetically) obese mice, even under uncontrolled food intake,” the researchers wrote. The drug also had effects on prostate cancer cells they said – something that may help explain links between prostate cancer and obesity.
Source: Reuters Health News
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